The VICC Meta-Knowledgebase


The Variant Interpretation for Cancer Consortium (VICC) meta-knowledgebase is a harmonized collection of clinical variant interpretations and related variant information informing of the clinical significance of variants observed in human cancers.

The meta-knowledgebase was created to evaluate the disparities in variant interpretation content and structure across established resources of clinical interpretation knowledge. The result of this work is described in full detail in our 2020 Nature Genetics publication.

This site is reference documentation for using the associated web interface for searching the meta-knowledgebase.

User Guide